ER-positivity

There is 1 paper on ER-positivity in aging research: 1 observational study in people.

Biomarker

1 paper studies it19 more mention it3 findings

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“Nulliparity and later age at menopause were associated with higher ER-positivity”
Clarifying risk-factor associations with quantitative breast tumor features: a pooled analysis of 24 studiesJournal of the National Cancer Institute2026doi:10.1093/jnci/djag244
  • Humans1

Associations

3

Body mass index

downin humans1

1 study
  1. Body mass index is associated with ER-positivity in humans (premenopausal women) (OR[ER+] 0.80 (0.74-0.87) per 5 units; p-trend<0.001).

    “Higher BMI was associated with lower ER-positivity and higher grade in premenopausal women”

    Humanspremenopausal womenbreast tumorper 5 BMI unitsfemales

    Clarifying risk-factor associations with quantitative breast tumor features: a pooled analysis of 24 studies

    Journal of the National Cancer Institute

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Age at menopause

upin humans1

1 study
  1. Age at menopause is associated with ER-positivity in humans (OR[ER+] 1.07 (1.03-1.11) per 5 years; p-trend=0.001).

    “Nulliparity and later age at menopause were associated with higher ER-positivity”

    Humansbreast tumor

    Clarifying risk-factor associations with quantitative breast tumor features: a pooled analysis of 24 studies

    Journal of the National Cancer Institute

More on Age at menopause

Nulliparity

upin humans1

1 study
  1. Nulliparity is associated with ER-positivity in humans (OR[ER+] 1.49 (1.16-1.90) for nulliparous vs. parous; p-trend=0.021).

    “Nulliparity and later age at menopause were associated with higher ER-positivity”

    Humansbreast tumor

    Clarifying risk-factor associations with quantitative breast tumor features: a pooled analysis of 24 studies

    Journal of the National Cancer Institute

More on Nulliparity

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