Tubulointerstitial fibrosis

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12 papers in 12 months

American Journal of NephrologyJan 3

A New Model of Chronic Kidney Disease, Metabolic Derangements, and Heart Failure with Preserved Ejection Fraction in Aging Swine

Experiments in pigsKidney

American Journal of Physiology Renal PhysiologyDec 9

Brown-Norway chromosome 1 mitigates the upregulation of proinflammatory pathways in mTAL cells and subsequent age-related CKD in Dahl SS/JrHsdMcwi rats

Experiments in ratsMechanisms

Zhongguo Zhong Yao Za ZhiOct 14

Effects and mechanisms of Supplemented Shenqi Dihuang Decoction Formula improving renal aging and tubulointerstitial fibrosis in diabetic kidney disease by inhibiting ferroptosis

Experiments in ratsSGLT2 inhibitors

Frontiers in MedicineSep 18

Necroptosis-senescence crosstalk in tubulointerstitial fibrosis: the mtDNA-cGAS-STING-PFKFB3 axis as a metabolic bridge

ReviewMechanisms

Clinical ScienceSep 3

IRAP deficiency preserves renal function and attenuates pathology in aged mice

Experiments in miceKidney

Preprints.orgJul 30

Targeting Inflammation in Chronic Kidney Disease: Pathophysiological Insights and Emerging Therapeutic Strategies

Preprint: reviewChronic kidney disease

BiologyJul 15

Fatty Kidney Disease: From Renal Lipid Dysregulation to Fibrosis

ReviewKidney

Cellular SignallingJun 22

Nicotinamide N-methyltransferase as a stress-responsive metabolic-epigenetic regulator of tubular senescence in chronic kidney disease

ReviewMethionine and one-carbon metabolism

American Journal of Physiology Renal PhysiologyMay 29

Pharmacologic disruption of HuR-RNA interactions prevents maladaptive tubular repair and AKI-to-CKD progression

Experiments in animalsMechanisms

Mechanisms of Ageing and DevelopmentMay 13

Targeting DYRK1A with harmine abrogates the FOXO1-NF-κB axis to alleviate cellular senescence and renal fibrosis

Study in peopleKidney