TTR aggregates

1. Alpha-santalol + beta-santalol decreases TTR aggregates in worms.

   “α- and β-santalol synergize to reduce wild-type (WT) and Val30Met (V30M) mutant TTR aggregates in novel C. elegans strains expressing TTR fragments fused with a green fluorescent protein”

   Model organismsin C. elegans expressing TTRWT::EGFP and TTRV30M::EGFP

   Santalol Isomers Inhibit Transthyretin Amyloidogenesis and Associated Pathologies in Caenorhabditis elegans

   Frontiers in pharmacology·Jun 16, 2022

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