Transcriptome conservation

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In silico1

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old-biasedgenes

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1 study

old-biasedgenes decrease transcriptome conservation in silico.
“age-related decrease in transcriptome conservation is commonly found in ageing tissues of nonmammalian species, including nonmammalian vertebrates (chicken brain, killifish liver and skin) and invertebrates (fruit fly brain)”
In silicobrain
Under the Shadow: Old-biased Genes Are Subject to Weak Purifying Selection at Both the Tissue- and Cell Type-Specific Levels
Genome biology and evolution30 Sep 2025

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Genome Biology and Evolution15 Oct

Under the Shadow: Old-biased Genes Are Subject to Weak Purifying Selection at Both the Tissue- and Cell Type-Specific Levels

Computational studyMechanisms