Toxic aggregation of circRNAs

1. RNASEK prevents toxic aggregation of circRNAs.

   “RNASEK, in collaboration with heat shock protein 90 (HSP90), prevents the toxic aggregation of circRNAs in aged organisms.”

   Animalswith heat shock protein 90 (HSP90) in stress granules

   Ribonuclease κ promotes longevity by preventing age-associated accumulation of circular RNA in stress granules

   Molecular cell·24 Feb 2026

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