Total ceramide content

1. SUR2 increases total ceramide content in yeast cells (SUR2 loss reduced total ceramide content to about half of wild-type).

   “resulting in a significant reduction of total ceramide content to about half of that in wild-type cells.”

   CellsShown by loss of SUR2 function versus wild-type cells

   Loss of SUR2 alters the composition of ceramides and shortens chronological lifespan of Saccharomyces cerevisiae

   Biochimica et biophysica acta. Molecular and cell biology of lipids·22 Dec 2024

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