Papers on tissue inhibitors of metalloproteinases

68 papers5 new in 30 days

Saturday, January 6

Molecular Biology ReportsJan 6

Sirt1 activation prevents high glucose-induced angiotensin converting enzyme 2 downregulation in renal tubular cells by regulating the TIMP3/ADAM17 pathway

Experiments in ratsKidney

Paper

Monday, December 18

Frontiers in Cellular NeuroscienceDec 18

A view of the genetic and proteomic profile of extracellular matrix molecules in aging and stroke

Experiments in miceExtracellular matrix

Paper

Saturday, October 28

Life SciencesOct 28

Targeting multiple disease hallmarks using a synergistic disease-modifying drug combination ameliorates osteoarthritis via inhibition of senescence and inflammation

Experiments in cellsOsteoarthritis

Paper

Friday, June 16

eNeuroJun 16

Noncanonical Activity of Tissue Inhibitor of Metalloproteinases 2 (TIMP2) Improves Cognition and Synapse Density in Aging

Experiments in miceInterventions

Paper

Friday, May 19

Annals of Geriatric Medicine and ResearchMay 19

Matrix Metalloproteinases/Tissue Inhibitors of Metalloproteinases Ratio: A Biomarker of Bone Resorption in Geriatric Osteoporosis?

Cross-sectional study of 87 peopleOsteoporosis

Paper

Wednesday, March 1

Aging CellMar 1

Glycation-mediated tissue-level remodeling of brain meningeal membrane by aging

Experiments in human cellsExtracellular matrix remodeling

Paper

Friday, December 16

Human CellDec 16

Induction of premature senescence and a less-fibrogenic phenotype by programmed cell death 4 knockdown in the human hepatic stellate cell line Lieming Xu-2

Experiments in human cellsCellular senescence

Paper

Sunday, November 27

International Journal of Molecular SciencesNov 27

Circulating Inflammatory, Mitochondrial Dysfunction, and Senescence-Related Markers in Older Adults with Physical Frailty and Sarcopenia: A BIOSPHERE Exploratory Study

Cross-sectional study in peopleSarcopenia

Paper

Saturday, July 23

Frontiers in Cardiovascular MedicineJul 23

Vascular Age, Metabolic Panel, Cardiovascular Risk and Inflammaging in Patients With Rheumatoid Arthritis Compared With Patients With Osteoarthritis

Cross-sectional study of 106 peopleRheumatoid arthritis

Paper

Thursday, May 19

Rejuvenation ResearchMay 19

Plasma Proteomic Signature of Cellular Senescence and Markers of Biological Aging Among Postmenopausal Women

Cross-sectional study of 76 peopleBiomarkers

Paper

Monday, February 28

TheriogenologyFeb 28

The onset of age-related benign prostatic hyperplasia is concomitant with increased serum and prostatic expression of VEGF in rats: Potential role of VEGF as a marker for early prostatic alterations

Experiments in 28 ratsVEGF

Paper

Thursday, June 10

European Geriatric MedicineJun 10

The relationship between primary sarcopenia and SARC-F, serum MMP9, TIMP1 levels, and MMP9/TIMP1 ratio in the geriatric patients

Cross-sectional study of 88 peopleMMP9

Paper

Tuesday, May 25

Journal of Ginseng ResearchMay 25

Saponins from Panax japonicus ameliorate age-related renal fibrosis by inhibition of inflammation mediated by NF-κB and TGF-β1/Smad signaling and suppression of oxidative stress via activation of Nrf2-ARE signaling

Experiments in animalsInterventions

Paper

Monday, May 17

Human ReproductionMay 17

The ellagic acid metabolites urolithin A and B differentially affect growth, adhesion, motility, and invasion of endometriotic cells in vitro

Experiments in human cellsUrolithin A

Paper

Sunday, March 7

International Journal of Molecular SciencesMar 7

Aged Skeletal Muscle Retains the Ability to Remodel Extracellular Matrix for Degradation of Collagen Deposition after Muscle Injury

Experiments in animalsExtracellular matrix remodeling

Paper

Thursday, February 25

Oxidative Medicine and Cellular LongevityFeb 25

Hormone Replacement Therapy and Aging: A Potential Therapeutic Approach for Age-Related Oxidative Stress and Cardiac Remodeling

Experiments in animalsInterventions

Paper

Wednesday, October 28

Vox SanguinisOct 28

The 'rejuvenating factor' TIMP-2 is detectable in human blood components for transfusion

Study in peopleMechanisms

Paper

Friday, May 8

Nan Fang Yi Ke Da Xue Xue BaoMay 8

Expressions of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinases 1 in skeletal muscles of aged rats with sarcopenia

Experiments in animalsMechanisms

Paper

Saturday, December 28

CellsDec 28

The Diverse Roles of TIMP-3: Insights into Degenerative Diseases of the Senescent Retina and Brain

ReviewMechanisms

Paper

Thursday, September 27

PlateletsSep 27

The effects of aging, diabetes mellitus, and antiplatelet drugs on growth factors and anti-aging proteins in platelet-rich plasma

Cross-sectional study in peopleMechanisms

Paper

Wednesday, July 18

Scientific ReportsJul 18

Amelioratory Effects of Testosterone Propionate on Age-related Renal Fibrosis via Suppression of TGF-β1/Smad Signaling and Activation of Nrf2-ARE Signaling

Experiments in ratsRenal fibrosis

Paper

Thursday, February 8

Aging CellFeb 8

Transcriptomics of aged Drosophila motor neurons reveals a matrix metalloproteinase that impairs motor function

Experiments in fliesMechanisms

Paper

Saturday, January 13

Biotechnic & HistochemistryJan 13

Age-related lung tissue remodeling due to the local distribution of MMP-2, TIMP-2, TGF-β and Hsp70

Study in peopleMechanisms

Paper

Saturday, December 9

BioFactorsDec 9

Less fibrosis in elderly subjects supplemented with selenium and coenzyme Q10-A mechanism behind reduced cardiovascular mortality?

Trial in peopleInterventions

Paper

Friday, July 7

Lasers in Medical ScienceJul 7

Photobiomodulation therapy action in wound repair skin induced in aged rats old: time course of biomarkers inflammatory and repair

Experiments in 45 ratsSkin

Paper

Monday, May 1

The Journal of Thoracic and Cardiovascular SurgeryMay 1

Pericardial interstitial cell senescence responsible for pericardial structural remodeling in idiopathic and postsurgical constrictive pericarditis

Study in peopleExtracellular matrix remodeling

Paper

Friday, April 21

NatureApr 21

Human umbilical cord plasma proteins revitalize hippocampal function in aged mice

Experiments in miceInterventions

Paper

Saturday, January 7

The American Journal of Sports MedicineJan 7

Effects of Platelet-Rich Plasma With Concomitant Use of a Corticosteroid on Tenocytes From Degenerative Rotator Cuff Tears in Interleukin 1β-Induced Tendinopathic Conditions

Experiments in human cellsPlatelet-rich plasma

Paper

Wednesday, November 16

Folia Histochemica et CytobiologicaNov 16

Potentially positive ageing-related variations of medial smooth muscle cells in the saphenous veins used as aortocoronary bypass grafts

Cross-sectional study of 216 peopleMechanisms

Paper

Saturday, September 17

Current Protein & Peptide ScienceSep 17

Cell Cycle Arrest as a Therapeutic Target of Acute Kidney Injury

ReviewCell cycle regulation

Paper