Thalamus volume

chronic low-grade inflammation decreases thalamus volume in humans (β = -0.053, 95% CI -0.073 to -0.033).

“thalamus (-0.053 [-0.073, -0.033])”

Humansn = 37,699

Chronic Low-Grade Inflammation and Brain Structure in the Middle-Aged and Elderly Adults

Nutrients·Jul 18, 2024

Thalamus volume is associated with gait speed decline in humans.

“Lower volumes in the thalamus and cerebellum were associated with a higher risk of gait only and cognitive only decline respectively.”

Humanscommunity-dwelling older adultsthalamusn = 266

Associations Between Regional Brain Volumes and Dual Decline in Gait Speed and Memory

AAIC 2025 abstract·Dec 24, 2025

Thalamus volume predicts hippocampal atrophy in humans (γ = -0.048 ± 0.015, P = 0.001, R 2 = 0.09).

“A larger baseline thalamus volume predicted slower hippocampal atrophy ( γ T → dH = - 0.048 ± 0.015 , P = 0.001 , R 2 = 0.09 )”

Humanscognitively unimpairedn = 653

Thalamus anatomy predicts cognitive performance and hippocampal atrophy in aging adults: a UK Biobank study

Brain communications·Sep 10, 2025

Thalamus volume is associated with cognitive function in humans (β = 0.055 ± 0.018, P = 0.002, R 2 = 0.09).

“Baseline thalamus volume was positively associated with the cognitive composite score ( β = 0.055 ± 0.018 , P = 0.002, R 2 = 0.09).”

Humanscognitively unimpairedn = 4,348

Thalamus anatomy predicts cognitive performance and hippocampal atrophy in aging adults: a UK Biobank study

Brain communications·Sep 10, 2025