T-tau

Biomarker1 paper

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Neurology Open AccessHumans

Epigenetic age links to higher dementia risk in older adults

In 2,606 participants, higher DunedinPACE was associated with increased risks of mild cognitive impairment (hazard ratio 1.16) and all-cause dementia…In 2,606 participants, higher DunedinPACE was associated with increased risks of mild cognitive impairment (hazard ratio 1.16) and all-cause dementia (hazard ratio 1.30).

Frontiers in Aging NeuroscienceHumans

High neutrophil-to-lymphocyte ratio predicts cognitive decline

During five years of follow-up, 42.55% of older adults with high ratios progressed to mild cognitive impairment or dementia compared with 30.82% with…During five years of follow-up, 42.55% of older adults with high ratios progressed to mild cognitive impairment or dementia compared with 30.82% with normal ratios.

Journal of Alzheimer's DiseaseHumans

Social isolation links to amyloid pathology and lower cognition

In 957 non-demented adults, social isolation was associated with lower cognitive scores, decreased cerebrospinal fluid amyloid-beta levels, and higher…In 957 non-demented adults, social isolation was associated with lower cognitive scores, decreased cerebrospinal fluid amyloid-beta levels, and higher tau-to-amyloid ratios.