Substance P

1 paper1 finding

Animals1

Interventions

1

Raloxifene

downin mice1

1 study

Raloxifene decreases substance P in mice.
“Raloxifene injections reduced mechanical sensitivity and IVD substance P in 4-month-old and 24-month-old mice of both sexes”
Animalsintervertebral disc4 weeks
Raloxifene injections normalize age-related mechanical sensitization in female and male mice and augment intervertebral disc structure in old female mice
Osteoarthritis and cartilage19 Mar 2026

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