1 paper1 finding
Mortality
downin humans1
Steroids are associated with mortality in humans.
“Notably, elevated levels of both bile acids and steroids were associated with lower mortality.”
Humans
Metabolomic signatures of extreme old age: findings from the New England Centenarian Study
GeroScience27 Mar 2026
An observational study of 353 adults aged 36–87 linked distinct brain patterns to later depression in younger women and blood markers of brain deterioration in older men.An observational study of 353 adults aged 36–87 linked distinct brain patterns to later depression in younger women and blood markers of brain deterioration in older men.
In 137 aging adults tracked across one year, changes in estradiol and testosterone showed opposing associations with cerebellar subregion volumes in men and women.In 137 aging adults tracked across one year, changes in estradiol and testosterone showed opposing associations with cerebellar subregion volumes in men and women.
In Mendelian randomization, plasma free asparagine showed an odds ratio of 0.852 for cardioembolic stroke, whereas the glutamine-to-asparagine ratio yielded an odds ratio…In Mendelian randomization, plasma free asparagine showed an odds ratio of 0.852 for cardioembolic stroke, whereas the glutamine-to-asparagine ratio yielded an odds ratio of 1.148.
In 5,535 women aged 70 and older, endogenous oestradiol concentrations showed no association with major cardiovascular events or all-cause mortality over 4.5 years of…In 5,535 women aged 70 and older, endogenous oestradiol concentrations showed no association with major cardiovascular events or all-cause mortality over 4.5 years of follow-up.