Somatic mutation limit

Bayesian DNA damage model predicts somatic mutation limit in silico (~3,000 somatic mutations/cell).

“quantitatively reproduces the observed human lifespan (~76 years) and the ~3,000 somatic mutations/cell limit observed in mammals.”

In silicoBayesian model using average literature values for DNA damage

Existing molecular biology indicates a path to biological immortality

Zenodo (CERN European Organization for Nuclear Research)·24 Jul 2026Preprint