Small insertion and deletion accumulation rate

Oligodendrocyte is associated with small insertion and deletion accumulation rate in humans (42% slower; 1.8/year versus 3.1/year).

“whereas indels accumulate 42% slower (1.8/year versus 3.1/year).”

Humanscompared with neurons in neurotypical individualsoligodendrocyte

Contrasting patterns of somatic mutations in neurons and glia reveal differential predisposition to disease in the aging human brain

bioRxiv : the preprint server for biology·Jan 14, 2023Preprint