SIRT2 deacetylase activity

1. Nicotinamide mononucleotide improves SIRT2 deacetylase activity in human cells.

   “The deacetylase activity of sirtuin (SIRT) 2 was improved with NMN treatment”

   CellsPD iPSC-derived dopaminergic neurons

   Nicotinamide mononucleotide treatment increases NAD+ levels in an iPSC Model of Parkinson’s Disease but does not impact sirtuin activity

   Research Square·Jul 22, 2020Preprint

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