Serum potassium
Biomarker1 paper2 findings
- Animals1
Interventions
1Rapamycin
downin mice1Very low certainty
1 study
Rapamycin
downin mice1Very low certainty
Rapamycin decreases serum potassium in mice.
Animalsin KLhet mice
Klotho deficiency disrupts potassium balance in mice · Acta physiologica (Oxford, England) · 5 Oct 2026
Upstream
1Klotho
downin mice1
1 study
Klotho
downin mice1
Klotho decreases serum potassium in mice.
Animalsin KLhet mice
Klotho deficiency disrupts potassium balance in mice · Acta physiologica (Oxford, England) · 5 Oct 2026
Latest
1Acta PhysiologicaAnimals
Klotho deficiency disrupts potassium balance in mice
In Klotho-deficient mice, renal mTORC1 activation suppressed potassium channel ROMK1 to cause hyperkalemia, which rapamycin or Klotho supplementation…In Klotho-deficient mice, renal mTORC1 activation suppressed potassium channel ROMK1 to cause hyperkalemia, which rapamycin or Klotho supplementation reversed.