Serum DHEA

1. Dehydroepiandrosterone increases serum DHEA in humans (levels found in normal premenopausal women).

   “Even at the highest 1.8% DHEA dose, serum DHEA was increased at the levels found in normal premenopausal women.”

   Human trialovule1.8%7 daysfemales

   Effect of intravaginal DHEA on serum DHEA and eleven of its metabolites in postmenopausal women

   The Journal of steroid biochemistry and molecular biology·Jun 12, 2008

More on Dehydroepiandrosterone

1. Pregnancy increases serum DHEA in D. bicornis (pregnant vs non-pregnant) (1092 ± 90.3 pg/ml vs 229 ± 8.1 pg/ml).

   “pregnant black rhinoceroses similarly produced elevated DHEA concentrations during pregnancy (1092 ± 90.3 pg/ml; n = 2) compared to non-pregnant (229 ± 8.1 pg/ml; n = 17) females”

   Animalspregnant vs non-pregnant

   Pregnancy- and age-associated variation in serum dehydroepiandrosterone concentrations in black and white rhinoceroses

   Conservation physiology·Feb 12, 2026

2. Pregnancy increases serum DHEA in C. simum (pregnant vs non-pregnant) (309 ± 31.9 pg/ml vs 120 ± 10.4 pg/ml, P < 0.001).

   “White rhinoceros DHEA concentrations were higher (P < 0.001) in pregnant (309 ± 31.9 pg/ml, n = 15) compared to non-pregnant (120 ± 10.4 pg/ml, n = 41) females”

   Animalspregnant vs non-pregnant

   Pregnancy- and age-associated variation in serum dehydroepiandrosterone concentrations in black and white rhinoceroses

   Conservation physiology·Feb 12, 2026

1. Increasing age is associated with serum DHEA in M. auratus (evening measurements) (about one-third of peak levels by one year of age).

   “Evening levels of DHEA and DHEAS reached a peak around 7 weeks of age and then gradually decreased to about one-third of these levels”

   Animalsevening measurementsserum

   Characterization of serum dehydroepiandrosterone secretion in golden hamsters

   Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)·Sep 1, 2000

1. time of day is associated with serum DHEA in M. auratus (evening compared with morning).

   “Hamsters had higher levels of DHEA and DHEAS in the evening than in the morning”

   Animalsevening compared with morningserum

   Characterization of serum dehydroepiandrosterone secretion in golden hamsters

   Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)·Sep 1, 2000

1. Serum DHEA is associated with breast cancer risk in humans (postmenopausal women).

   “Epidemiological studies report a positive correlation between higher serum concentrations of DHEA and increased breast cancer risk in the case of postmenopausal but not premenopausal women.”

   Reviewpostmenopausal womenfemales

   Dietary supplements of dehydroepiandrosterone in relation to breast cancer risk

   European journal of clinical nutrition·Oct 1, 1999