Serum α-Klotho

1. Binge drinking is associated with serum α-Klotho in humans (-9.17%; P = .0341).

   “binge drinking ≥ 4 days in the past month was associated with a 9.17% (P = .0341) decrease in serum ɑ-Klotho.”

   Humansserum≥ 4 days in the past monthn = 4,225

   Decreases in serum α-Klotho levels in association with levels of regular alcohol drinking and binge drinking among US adults

   Alcohol and alcoholism (Oxford, Oxfordshire)·16 Jul 2025

More on Binge drinking

1. Alcohol is associated with serum α-Klotho in humans (-6.53%; P < .0001).

   “After adjusting for covariates, moderate drinking was associated with a 6.53% (P < .0001) decrease”

   HumansModerate drinking versus non-drinking; adjusted for covariatesserum3-4 drinks for men and 2-3 drinks for women in a dayn = 4,225

   Decreases in serum α-Klotho levels in association with levels of regular alcohol drinking and binge drinking among US adults

   Alcohol and alcoholism (Oxford, Oxfordshire)·16 Jul 2025

More on Alcohol