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Senescence and SASP marker gene expression

There are 2 papers on senescence and SASP marker gene expression in aging research: none in people yet, 1 in animals, 1 in cells.

Biomarker

2 papers study it1 finding

See all 2 papers on senescence and SASP marker gene expression

  • Animals1
  • Cells1

Interventions

1

Phosphatidic acid

downin mouse cells1

1 study

  1. Phosphatidic acid decreases senescence and SASP marker gene expression in mouse cells (wild-type SV cells).

    “downregulated of senescence and senescence-associated secretory phenotype (SASP) marker genes, including p16, Cebpb, Il1b, Il18, and Tnfa”

    Cellswild-type SV cellsPA 16:0 18:1 or PA 16:0 18:2stromal-vascular cells from inguinal white adipose tissuetwo days

    Lipocalin-2 Regulates the Function of Phosphatidic Acid in Senescence and mTOR Signaling in Adipose Stromal-Vascular Cells

    ADA Scientific Sessions 2025 abstract

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