SARS-CoV-2 antibodies

1. COVID-19 vaccines are linked with higher SARS-CoV-2 antibodies in humans across all ages.

   “Two vaccine doses achieved high responses across all ages.”

   Humansacross all agestwo vaccine doses

   Antibody responses to SARS-CoV-2 vaccines in 45,965 adults from the general population of the United Kingdom

   Nature microbiology·Jul 21, 2021

More on COVID-19 vaccines

1. Older age is linked with higher SARS-CoV-2 antibodies in humans.

   “The age group ≥90 years had higher levels of antibodies than that <65 years.”

   Humans

   Cross-sectional Characterization of SARS-CoV-2 Antibody Levels and Decay Rates Following Infection of Unvaccinated Elderly Individuals

   Open forum infectious diseases·Jul 20, 2023

1. Oldest-old is linked with lower SARS-CoV-2 antibodies in nursing home residents.

   “Alternatively, age ≥ 80 years old, the presence of comorbidities and high care dependency predicted SARS-CoV-2 seronegativity in NHR.”

   Humansin nursing home residents

   Prevalence of SARS-CoV-2 antibodies among Belgian nursing home residents and staff during the primary COVID-19 vaccination campaign

   The European journal of general practice·Nov 28, 2022

1. Older-adults are linked with lower SARS-CoV-2 antibodies in fully vaccinated individuals (77% vs 98%).

   “fewer residents tested positive for SARS-CoV-2 antibodies (77%) than staff (98%), suggesting an impaired vaccine-induced antibody response in the elderly”

   Humansin fully vaccinated individuals

   Prevalence of SARS-CoV-2 antibodies among Belgian nursing home residents and staff during the primary COVID-19 vaccination campaign

   The European journal of general practice·Nov 28, 2022

1. Age is linked with lower SARS-CoV-2 antibodies in humans (no prior infection with SARS-CoV-2).

   “seroconversion rates and quantitative antibody levels after a single dose were lower in older individuals, especially in those aged >60 years”

   Humansno prior infection with SARS-CoV-2single dose

   Antibody responses to SARS-CoV-2 vaccines in 45,965 adults from the general population of the United Kingdom

   Nature microbiology·Jul 21, 2021

1. Age is associated with SARS-CoV-2 antibodies in humans (convalescent COVID-19 outpatients).

   “Serum antibody concentration was positively associated with microneutralization activity and participant age, with participants under the age of 30 showing the lowest antibody level.”

   Humansconvalescent COVID-19 outpatients

   SARS-CoV-2 Antibody Response is Associated with Age in Convalescent Outpatients

   medRxiv : the preprint server for health sciences·Nov 8, 2021Preprint