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RNA G-quadruplexes

Biomarker

3 papers9 findings

  • Humans3

Effects

1

Tau aggregation

upin humans2

2 studies

  1. RNA G-quadruplexes induce tau aggregation in humans.

    “rG4 structure can drive tau aggregation”

    Humanshippocampus

    Chronic RNA G-quadruplex accumulation in aging and Alzheimer's disease

    eLifeFeb 24, 2025

  2. RNA G-quadruplexes induce tau aggregation in humans.

    “rG4 structure can drive tau aggregation”

    Humans

    Chronic RNA G-quadruplex Accumulation in Aging and Alzheimer’s Disease

    eLifeFeb 3, 2025Preprint

Associations

3

APOE

upin humans2mixedin humans1

3 studies

  1. APOE is associated with RNA G-quadruplexes in humans.

    “rG4 staining density depended on APOE genotype in the human tissue examined”

    Humanshippocampus

    Chronic RNA G-quadruplex accumulation in aging and Alzheimer's disease

    eLifeFeb 24, 2025

  2. APOE is associated with RNA G-quadruplexes in humans.

    “rG4 staining density depended on APOE genotype in the human tissue examined.”

    Humanshippocampus

    Chronic RNA G-quadruplex Accumulation in Aging and Alzheimer’s Disease

    eLifeFeb 3, 2025Preprint

  3. APOE is associated with RNA G-quadruplexes in humans.

    “rG4 staining density depended on APOE genotype in the human tissue examined.”

    Humanshippocampus

    A New Role for RNA G-quadruplexes in Aging and Alzheimer’s Disease

    eLifeJan 14, 2025Preprint

More on APOE

Alzheimer's disease

upin humans3

3 studies

  1. Alzheimer's disease is associated with RNA G-quadruplexes in humans.

    “rG4 immunostaining strongly increased in the hippocampus with both age and with AD severity”

    Humanshippocampus

    Chronic RNA G-quadruplex accumulation in aging and Alzheimer's disease

    eLifeFeb 24, 2025

  2. Alzheimer's disease is associated with RNA G-quadruplexes in humans.

    “rG4 immunostaining strongly increased in the hippocampus with both age and with AD severity.”

    Humanshippocampus

    Chronic RNA G-quadruplex Accumulation in Aging and Alzheimer’s Disease

    eLifeFeb 3, 2025Preprint

  3. Alzheimer's disease is associated with RNA G-quadruplexes in humans.

    “rG4 immunostaining strongly increased in the hippocampus with both age and with AD severity.”

    Humanshippocampus

    A New Role for RNA G-quadruplexes in Aging and Alzheimer’s Disease

    eLifeJan 14, 2025Preprint

More on Alzheimer's disease

Age

upin humans1

1 study

  1. Age is associated with RNA G-quadruplexes in humans.

    “rG4 immunostaining strongly increased in the hippocampus with both age and with AD severity”

    Humanshippocampus

    Chronic RNA G-quadruplex accumulation in aging and Alzheimer's disease

    eLifeFeb 24, 2025

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