RNA G-quadruplex immunostaining

1. Alzheimer's disease increases RNA G-quadruplex immunostaining in humans.

   “We found that rG4 immunostaining strongly increased in the hippocampus with both age and with AD severity.”

   Humanshippocampus

   Chronic RNA G-quadruplex Accumulation in Aging and Alzheimer's Disease

   bioRxiv : the preprint server for biology·Oct 24, 2023Preprint

More on Alzheimer's disease

1. APOE is associated with RNA G-quadruplex immunostaining in humans.

   “rG4 staining density depended on APOE genotype in the human tissue examined.”

   Humanshippocampus

   Chronic RNA G-quadruplex Accumulation in Aging and Alzheimer's Disease

   bioRxiv : the preprint server for biology·Oct 24, 2023Preprint

More on APOE