Rapamycin blood concentration

Rapamycin blood concentration is associated with skeletal muscle density in humans (r=0.64).

“higher rapamycin blood concentration was significantly correlated with greater skeletal muscle density (r=0.64, p=0.035)”

Human trialExposure-response analysis in early-stage Alzheimer's diseaseskeletal muscle7 mg once weekly26 weeks

Multi-modal and multi-organ in vivo imaging to assess geroprotective interventions in humans: results from a pilot trial of rapamycin in Alzheimer’s Disease

medRxiv·12 Mar 2026Preprint