There are 8 papers on putamen volume in aging research: 7 observational studies in people. The newest story, Oct 8, 2026: “Higher blood pressure is linked to larger brain structures”.
8 papers study it13 more mention it3 findings
1 new paper in 30 daysSee all 21
“Putamen emerged as a key structure linked with both fatigue (r = -.43, P = .003) and TMT B-A (β = .35, P = .021).”
Surgery with general anesthesia
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Surgery with general anesthesia is linked with lower putamen volume in humans (p < 0.05).
“older adults with a history of surgery under general anesthesia had lower Montreal Cognitive Assessment (MoCA) scores and smaller right putamen volumes (p < 0.05).”
Humansputamenn = 194
Frontiers in aging neuroscience
Fatigue
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Putamen volume is associated with fatigue in humans (r = -.43, P = .003).
“Putamen emerged as a key structure linked with both fatigue (r = -.43, P = .003) and TMT B-A (β = .35, P = .021).”
Humansn = 48
Structural Basal Ganglia Correlates of Subjective Fatigue in Middle-Aged and Older Adults
Journal of geriatric psychiatry and neurology
Baseline putamen iron content
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Baseline putamen iron content predicts putamen volume in humans (healthy middle-aged and older adults).
“Moreover, greater baseline iron content predicted faster shrinkage and smaller volumes seven years later.”
Humanshealthy middle-aged and older adultsputamen7 yearsn = 32
NeuroImage
In an analysis of 1,012 participants, higher blood pressure was linked to larger deep brain volumes compared with blood pressure below 120/80 millimeters of mercury.In an analysis of 1,012 participants, higher blood pressure was linked to larger deep brain volumes compared with blood pressure below 120/80 millimeters of mercury.