Proteome signatures associated with AD development

1. Down syndrome induces proteome signatures associated with AD development in humans.

   “Our data support a genotype effect in DS at young and old ages that promotes specific proteome signatures associated with AD development.”

   HumansDown syndromefrontal cortex

   Proteome Signature of Alzheimer-Like Phenotypes in Frontal Cortices From Young and Old Individuals With Down Syndrome

   Molecular neurobiology·21 Nov 2025

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