Proteoglycan matrix content

1. Ganciclovir increases proteoglycan matrix content in mice.

   “increased overall proteoglycan matrix content along with improved histological disc features”

   Animalsp16-3MR mice treated with ganciclovirintervertebral disc

   Systemic clearance of p16INK4a -positive senescent cells mitigates age-associated intervertebral disc degeneration

   Aging cell·21 Mar 2019

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