Protein associations

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Polygenic risk scores

upin humans1

1 study
  1. polygenic risk scores are associated with protein associations in humans (90 protein associations).

    Humansacross 21 cancers

    Polygenic risk scores and plasma proteomics identify cancer-related proteins and trans-regulated protein networks

    Cell genomics7 Aug 2026

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bioRxiv

Aging alters eye tissue proteins differently in mice

In an experiment comparing 73-week-old mice with 8-week-old mice, aging changed 85 proteins in the retina and 272 in the supporting eye tissue.In an experiment comparing 73-week-old mice with 8-week-old mice, aging changed 85 proteins in the retina and 272 in the supporting eye tissue.

Preprint: experiments in miceEye
medRxiv

Blood proteins predict physical rehab gains in older adults

Baseline protein profiles stratified 12-week physical gains from rehabilitation over control, spanning 10 to 85 meters on the six-minute walk test.Baseline protein profiles stratified 12-week physical gains from rehabilitation over control, spanning 10 to 85 meters on the six-minute walk test.

Preprint: randomised trial in 243 peopleInterventions
medRxiv

Plasma proteomics reveals pre-diagnostic markers for 25 cancers

In a study of 9,828 participants, researchers identified 1,732 plasma protein associations across 25 cancers, with 49% statistically replicated in an independent cohort.In a study of 9,828 participants, researchers identified 1,732 plasma protein associations across 25 cancers, with 49% statistically replicated in an independent cohort.

Preprint: cohort study of 9,828 peopleCancer
Diabetes, Obesity & Metabolism

Blood proteins improve early cardiometabolic risk prediction

In 43,709 adults with early-stage disease, outcome-specific proteomic signatures improved clinical risk discrimination across 11 incident outcomes, boosting C-index…In 43,709 adults with early-stage disease, outcome-specific proteomic signatures improved clinical risk discrimination across 11 incident outcomes, boosting C-index values by 0.024 to 0.070.

Cohort study of 43,709 peopleBiomarkers