There are 7 papers on pregnenolone in aging research: 3 observational studies in people, 3 in animals, 1 in cells.
See all 15 papers on pregnenolone
- Humans3
- Animals3
- Cells1
Interventions
1Human umbilical cord-derived mesenchymal stem cells
upin mice1
1 study
Human umbilical cord-derived mesenchymal stem cells
upin mice1
Human umbilical cord-derived mesenchymal stem cells increase pregnenolone in mice.
“Mechanistically, HucMSCs promoted pregnenolone synthesis in stromal cells, facilitating follicular development.”
Animalsovary
Cellular & molecular biology letters
Latest
2 papers in 12 monthsCellular & Molecular Biology Letters
HucMSC-mediated stromal metabolic reprogramming in reactivating aged ovaries: a single-cell transcriptomic perspective
Experiments in miceReproductive system
ENDO 2025 Abstract
SAT-262 Sex-Specific Effects of Statins on Cholesterol and Steroid Metabolism in Dyslipidemia: Implications for Androgen Biosynthesis
Cohort study in peopleStatins
Cancer Epidemiology, Biomarkers & Prevention
Association of Endogenous Pregnenolone, Progesterone, and Related Metabolites with Risk of Endometrial and Ovarian Cancers in Postmenopausal Women: The B∼FIT Cohort
Cohort study of 413 peopleReproductive system
Clinica Chimica Acta; International Journal of Clinical Chemistry
Reference intervals for plasma concentrations of adrenal steroids measured by LC-MS/MS: Impact of gender, age, oral contraceptives, body mass index and blood pressure status
Cross-sectional study of 525 peopleBiomarkers
The Journal of Clinical Endocrinology and Metabolism
Stromal cells of the human postmenopausal ovary display a distinctive biochemical and molecular phenotype
Experiments in human cellsReproductive system
European Journal of Endocrinology
Circadian rhythms of 11-oxygenated C19 steroids and ∆5-steroid sulfates in healthy men
Cohort study in peopleMechanisms