PpgAge gap

1. PpgAge gap predicts heart disease in humans.

   “Elevated PpgAge gap is also a significant predictor of incident heart disease events (and new diagnoses) when controlling for relevant risk factors.”

   Humanscontrolling for relevant risk factors

   A wearable-based aging clock associates with disease and behavior

   Nature communications·20 Oct 2025

2. PpgAge gap is associated with heart disease in humans.

   “Participants with an elevated PpgAge gap (i.e., predicted age greater than chronological age) have significantly higher diagnosis rates of heart disease, heart failure, and diabetes.”

   Humanselevated PpgAge gap

   A wearable-based aging clock associates with disease and behavior

   Nature communications·20 Oct 2025

More on Heart disease

1. PpgAge gap is associated with diabetes in humans.

   “Participants with an elevated PpgAge gap (i.e., predicted age greater than chronological age) have significantly higher diagnosis rates of heart disease, heart failure, and diabetes.”

   Humanselevated PpgAge gap

   A wearable-based aging clock associates with disease and behavior

   Nature communications·20 Oct 2025

More on Diabetes

1. PpgAge gap is associated with heart failure in humans.

   “Participants with an elevated PpgAge gap (i.e., predicted age greater than chronological age) have significantly higher diagnosis rates of heart disease, heart failure, and diabetes.”

   Humanselevated PpgAge gap

   A wearable-based aging clock associates with disease and behavior

   Nature communications·20 Oct 2025

More on Heart failure