POLD1 expression
2 papers2 findings
- Animals1
- Cells1
Interventions
1Insulin-like growth factor 1
downin human cells1
1 study
Insulin-like growth factor 1
downin human cells1
Insulin-like growth factor 1 decreases POLD1 expression in human cells.
“the cells cultured with old-age human serum or IGF-1 showed lower POLD1 expression and more pronounced senescence characteristics”
Cells2BS cells
IGF-1 Accelerates Cell Aging by Inhibiting POLD1 Expression
Biomedical and environmental sciences : BES20 Nov 2022
Upstream
1KLF14
upin cells1
1 study
KLF14
upin cells1
KLF14 increases POLD1 expression in cells.
“KLF14 delays aging by binding to the POLD1 promoter to positively regulate POLD1 expression.”
Cells
Downregulation of KLF14 accelerated cellular senescence and aging
Research Square26 Jan 2023Preprint
Latest
Aging Cell
Downregulation of Krüppel-like factor 14 accelerated cellular senescence and aging
Experiments in animalsMechanisms
Research Square
Downregulation of KLF14 accelerated cellular senescence and aging
Preprint: experiments in miceCellular senescence
Biomedical and Environmental Sciences
IGF-1 Accelerates Cell Aging by Inhibiting POLD1 Expression
Experiments in human cellsIGF1