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PhenoAge acceleration and BioAge acceleration

Biomarker

1 paper2 findings

  • Humans1

Interventions

1

Sleep duration

downin humans1

1 study

  1. Sleep duration decreases PhenoAge acceleration and BioAge acceleration in humans.

    “a threshold nonlinear relationship between increasing genetically-predicted sleep duration up to 7 h/d and lower PhenoAgeAccel/BioAgeAccel”

    HumansMendelian randomization; threshold nonlinear relationshipgenetically predictedIncreasing sleep duration up to 7 h/dn = 442,664

    Evaluating the nonlinear effects of sleep duration on biological aging across phenotypic, genomic, and epigenomic data

    Aging25 Aug 2025

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Associations

1

Sleep duration

mixedin humans1

1 study

  1. Sleep duration is associated with PhenoAge acceleration and BioAge acceleration in humans.

    “Observational analyses supported U-shaped phenotypic associations between sleep duration and PhenoAgeAccel/BioAgeAccel, with optimal sleep around 7 h/d.”

    HumansObservational analysis; U-shaped associations with optimal sleep around 7 h/dself-reportedn = 442,664

    Evaluating the nonlinear effects of sleep duration on biological aging across phenotypic, genomic, and epigenomic data

    Aging25 Aug 2025

More on Sleep duration

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