Percentage of short telomeres

1. Astragalus decreases percentage of short telomeres in humans.

   “The percentage of short telomeres tended to decrease in the placebo group (p = 0.16), but significantly decreased in the ASTCOQ02 group at 6 months (6.645 ± 3.680% at baseline versus 4.870 ± 1.468% at 6 months; p = 0.04; ).”

   Human trialsix monthsn = 40

   A Natural Astragalus-Based Nutritional Supplement Lengthens Telomeres in a Middle-Aged Population: A Randomized, Double-Blind, Placebo-Controlled Study

   Nutrients·Sep 3, 2024

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1. Age increases percentage of short telomeres in rats (no increase in brain).

   “The percentage of short telomeres increased with age in the kidney, liver, pancreas and lung of both males and females, but not in the brain.”

   Animalsno increase in brainkidney, liver, pancreas, lung

   Ageing and telomeres: a study into organ- and gender-specific telomere shortening

   Nucleic acids research·Mar 1, 2003

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1. Percentage of short telomeres predict lifespan in wild-type and transgenic telomerase reverse transcriptase mice.

   “the rate of increase in the percentage of short telomeres, rather than the rate of telomere shortening per month, was a significant predictor of lifespan in both mouse cohorts”

   Animalsin wild-type and transgenic telomerase reverse transcriptase mice

   The rate of increase of short telomeres predicts longevity in mammals

   Cell reports·Sep 27, 2012