PDGFRB signal

Biomarker

1 paper1 finding

Humans1

Associations

Cerebral small vessel disease severity

downin humans1

1 study

Cerebral small vessel disease severity is associated with PDGFRB signal in humans.
“At the molecular level, PDGFRβ signal decreased markedly with increasing cSVD severity, consistent with reduced pericyte coverage.”
Humansacross cerebral small vessel disease severitycortical grey matter and white mattern = 20
Human brain vessels show distinct states in small vessel disease
Acta neuropathologica13 Oct 2026

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Acta Neuropathologica1 h

Human brain vessels show distinct states in small vessel disease

Researchers identified three vessel states across disease severity by analysing 11,409 vessel fragments from post-mortem brain tissue from 20 cases.Researchers identified three vessel states across disease severity by analysing 11,409 vessel fragments from post-mortem brain tissue from 20 cases.

Cross-sectional study of 20 peopleMechanisms

Paper

PDGFRB signal

Associations

Latest

Human brain vessels show distinct states in small vessel disease

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