Chemico-biological Interactions·Oct 2Benzophenone-3 drives osteoarthritis pathogenesis by regulating chondrocyte senescenceExperiments in ratsCellular senescencePaper
JOR Spine·Jul 3Mechanistic Interactions Driving Nucleus Pulposus Cell Senescence in Intervertebral Disc Degeneration: A Multi-Axial Perspective of Mechanical, Immune, and Metabolic PathwaysReviewImmune responsePaper
Nature Communications·Jul 2The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRIExperiments in human cellsTP53Paper
Advanced Science·Jan 5Engineered MSC-sEVs as a Versatile Nanoplatform for Enhanced Osteoarthritis Treatment via Targeted Elimination of Senescent Chondrocytes and Maintenance of Cartilage Matrix Metabolic HomeostasisExperiments in miceOsteoarthritisPaper
Toxicology·Apr 15The novel polyfluoroalkyl benzenesulfonate OBS exposure induces cell cycle arrest and senescence of rat pituitary cell GH3 via the p53/p21/RB pathwayExperiments in rat cellsp53–p21 pathwayPaper
Heliyon·Mar 15Antioxidants prevent particulate matter-induced senescence of lung fibroblastsExperiments in human cellsLungPaper
Heliyon·Feb 25A novel role of Fas in delaying cellular senescenceExperiments in mouse cellsCellular senescencePaper
International Journal of Molecular Sciences·Dec 17Dapagliflozin Prevents High-Glucose-Induced Cellular Senescence in Renal Tubular Epithelial CellsExperiments in human cellsDapagliflozinPaper
Cytokine·Sep 3RANKL down-regulates the mast cell proliferation through inducing senescenceExperiments in human cellsCellular senescencePaper
bioRxiv·Apr 53’UTR-dependent dynamic changes in TP53 mRNA localization regulate p53 tumor suppressor activityPreprint: experiments in human cellsTP53Paper
Nature Communications·Aug 19ZNF768 links oncogenic RAS to cellular senescenceExperiments in human cellsCellular senescencePaper
Cancer Research·Dec 1Balancing and Differentiating p53 Activities toward Longevity and No Cancer?CommentaryTP53Paper
Aging·Nov 5Nucleolar stress induces a senescence-like phenotype in smooth muscle cells and promotes development of vascular degenerationExperiments in animalsMechanismsPaper
Free Radical Biology & Medicine·Aug 10Exercise-mediated downregulation of MALAT1 expression and implications in primary and secondary cancer preventionTrial in peopleInterventionsPaper
Free Radical Biology & Medicine·Apr 29Early induction of senescence and immortalization in PGC-1α-deficient mouse embryonic fibroblastsExperiments in cellsMechanismsPaper
PLOS One·Mar 15Mycophenolic acid induces senescence of vascular precursor cellsExperiments in cellsInterventionsPaper
FASEB Journal·Jun 20Excess centrosomes induce p53-dependent senescence without DNA damage in endothelial cellsExperiments in human cellsDNA damage responsePaper
Cancer Research·Sep 16BTK Modulates p53 Activity to Enhance Apoptotic and Senescent ResponsesExperiments in cellsDNA damage responsePaper
Cell Biochemistry and Function·May 24Accumulation of apoptosis-insensitive human bone marrow-mesenchymal stromal cells after long-term expansionExperiments in human cellsApoptosisPaper
Cell Cycle·Jun 13Soothing the watchman: telomerase reduces the p53-dependent cellular stress responseExperiments in human cellsTelomerase and telomere maintenancePaper