P16 INK4a, P21 Cip1 and P53 expression
1 paper1 finding
- Animals1
Interventions
1CXCL10
upin mice1
1 study
CXCL10
upin mice1
CXCL10 increases P16 INK4a, P21 Cip1 and P53 expression in mice.
“We observed increased expression of senescent marker proteins p16 INK4a , p21 Cip1 , p53”
AnimalsC57BL/6J mice; intracerebroventricular infusionprefrontal cortex0.5 pg/ hrs28 days
CXCL10/CXCR3 Signaling Induces Neural Senescence and Cognitive Impairments
bioRxiv (Cold Spring Harbor Laboratory)18 Oct 2024Preprint
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bioRxiv
CXCL10/CXCR3 Signaling Induces Neural Senescence and Cognitive Impairments
Preprint: experiments in miceSynaptic transmission