P16 INK4a, P21 Cip1 and P53 expression

Biomarker

1 paper1 finding

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CXCL10

upin mice1

1 study
  1. CXCL10 increases P16 INK4a, P21 Cip1 and P53 expression in mice.

    “We observed increased expression of senescent marker proteins p16 INK4a , p21 Cip1 , p53”

    AnimalsC57BL/6J mice; intracerebroventricular infusionprefrontal cortex0.5 pg/ hrs28 days

    CXCL10/CXCR3 Signaling Induces Neural Senescence and Cognitive Impairments

    bioRxiv (Cold Spring Harbor Laboratory)18 Oct 2024Preprint

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