Nitric oxide synthase

Biomarker

2 papers2 findings

MeSH D019001

  • Human trial1
  • Model organisms1

Interventions

2

Heat

upin A. gambiae1

1 study
  1. Heat increases nitric oxide synthase in A. gambiae.

    “in mosquitoes infected with bacteria, warmer temperature increases the activity of nitric oxide synthase”

    Model organismsin mosquitoes infected with bacteria

    In mosquitoes, warmer temperature reverses the aging-dependent decrease in nitric oxide synthase activity, modifying the expression of oxidative stress and immune genes

    Developmental and comparative immunology20 Jan 2026

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Acarbose

upin humans1

1 study
  1. Acarbose increases nitric oxide synthase in humans.

    “serum NO levels and NOS activities were also significantly increased and were positively related to GLP-1 levels.”

    Human trialin patients with increased postprandial GLP-1 levelsserum268 mg daily24 weeks

    Effects of 24-week treatment with acarbose on glucagon-like peptide 1 in newly diagnosed type 2 diabetic patients: a preliminary report

    Cardiovascular diabetology4 May 2013

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American Journal of Physiology Heart and Circulatory Physiology

Mitochondrial proteostasis is impaired in mouse heart failure

Aged mice on a high-fat diet and L-NAME showed impaired mitochondrial proteostasis rather than defective biogenesis, suggesting quality control may contribute to reduced…Aged mice on a high-fat diet and L-NAME showed impaired mitochondrial proteostasis rather than defective biogenesis, suggesting quality control may contribute to reduced cardiac reserve.

Experiments in miceProteostasis