Nevus count polygenic risk score

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Acral lentiginous melanoma risk

upin humans1

1 study
  1. Nevus count polygenic risk score is associated with acral lentiginous melanoma risk in humans.

    “A nevus count PRS was associated with acral lentiginous melanoma risk, the first evidence of a germline genetic effect on this rare melanoma subtype.”

    Humans

    Melanoma risk linked to immune and cancer-related genes

    medRxiv15 Oct 2026Preprint

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medRxiv

Melanoma risk linked to immune and cancer-related genes

An analysis of 69,871 melanoma cases and 1,616,233 comparison participants identified 156 independent genetic signals in 116 regions linked to risk.An analysis of 69,871 melanoma cases and 1,616,233 comparison participants identified 156 independent genetic signals in 116 regions linked to risk.

Preprint: study in peopleCutaneous melanoma