Melanoma polygenic risk score

Biomarker

1 paper1 finding

Humans1

Associations

Melanoma risk

upin humans1

1 study

Melanoma polygenic risk score predicts melanoma risk in humans (AUC above 0.70).
“We developed and validated a new melanoma PRS in two cohorts, improving discrimination beyond age and sex, achieving an AUC above 0.70.”
Humansvalidated in two cohorts; discrimination beyond age and sex
Melanoma risk linked to immune and cancer-related genes
medRxiv15 Oct 2026Preprint

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medRxiv2 h

Melanoma risk linked to immune and cancer-related genes

An analysis of 69,871 melanoma cases and 1,616,233 comparison participants identified 156 independent genetic signals in 116 regions linked to risk.An analysis of 69,871 melanoma cases and 1,616,233 comparison participants identified 156 independent genetic signals in 116 regions linked to risk.

Preprint: study in peopleCutaneous melanoma

Paper

Melanoma polygenic risk score

Associations

Latest

Melanoma risk linked to immune and cancer-related genes

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