Naïve B cells

Biomarker

2 papers1 finding

Humans1
Animals1

Associations

Cognitively impaired no dementia

downin humans1HR 0.92

1 study

Naïve B cells lower the risk of cognitively impaired no dementia in humans (HR = 0.92, 95% CI: 0.87-0.98).
“naïve B cells independently predicted reduced cognitive impairment risk after full covariate adjustment (HR = 0.92, 95% CI: 0.86-0.98 and HR = 0.92, 95% CI: 0.87-0.98).”
Humansn = 4,464
Immune cell profiles predict cognitive decline in older adults
Age and ageing1 Sep 2026

More on Cognitively impaired no dementia

Latest

5 in 12 months

Age and Ageing29 Sep

Immune cell profiles predict cognitive decline in older adults

In 4,464 cognitively normal older adults, a higher immune risk score predicted incident cognitive impairment or dementia with a hazard ratio of 1.63 over six years.In 4,464 cognitively normal older adults, a higher immune risk score predicted incident cognitive impairment or dementia with a hazard ratio of 1.63 over six years.

Cohort study of 9,008 peopleBiomarkers

Paper

Journal of Autoimmunity28 Aug