mTORC1 activation
1 paper
- Animals1
Latest
10 in 12 monthsbioRxiv
Hormetic heat shock activates HLH-30/TFEB independently of canonical nutrient-sensing pathways
Preprint: experiments in wormsMechanisms
Experimental Gerontology
Aging preserves mTORC1 but attenuates JNK-SMAD2L signaling sensitivity to passive stretch-induced tension development in isolated mouse skeletal muscle
Experiments in animalsJNK signalling
Signal Transduction and Targeted Therapy
Hyperglutaminolysis drives senescence and aging through arginine-mTORC1 axis activation
Experiments in fliesmTOR signalling
bioRxiv
Lung progenitors’ exhaustion in response to microenvironment stress during aging
Preprint: experiments in animalsStem cell maintenance
Food Research International
A comparative study of the effects of high protein diets of soy and dairy on healthy aging by integrating multi-omics approaches
Cohort study in peopleInterventions
Dermatologic Surgery
RLX-201, a Novel mTORC1 Inhibitor With Potential to Promote Skin Longevity and Cellular Health
Experiments in human cellsmTOR inhibitors