mt-Nd4 expression

1. Mitochondrial epigenetic editor decreases mt-Nd4 expression in mice.

   “leading to reduced MT-ND4 expression in the targeted brain region and altered plasma levels of t-Tau and NFL in mice.”

   AnimalsMethylation targeting C11168 (H)targeted brain region

   Programmable aging function-related mitochondrial DNA 5-methylcytosine (m5C) modification with a TALE-directed methyltransferase

   Cell communication and signaling : CCS·27 Jun 2026

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