Mitochondrial protein acetylation

2 papers4 findings

Animals2

Upstream

1

SIRT3

downin mice1

1 study

SIRT3 decreases mitochondrial protein acetylation in mice.
“SIRT3 is a prominent regulator in CR adaptation by coordinately deacetylating proteins involved in diverse pathways of metabolism and mitochondrial maintenance”
Animalsduring caloric restrictionliver
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome
Molecular cell29 Nov 2012

Associations

2

Caloric restriction

mixedin animals1mixedin mice1

2 studies

Caloric restriction is associated with mitochondrial protein acetylation in mice.
“reveal widespread reprogramming of mitochondrial protein acetylation in response to CR and SIRT3”
Animalsliver
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome
Molecular cell29 Nov 2012
Caloric restriction is associated with mitochondrial protein acetylation.
“lysine acetylation of mitochondrial proteins is altered during CR in a tissue-specific fashion.”
Animals
Calorie restriction alters mitochondrial protein acetylation
Aging cell9 Jul 2009

More on Caloric restriction

SIRT3

mixedin mice1

1 study

SIRT3 is associated with mitochondrial protein acetylation in mice.
“reveal widespread reprogramming of mitochondrial protein acetylation in response to CR and SIRT3”
Animalsliver
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome
Molecular cell29 Nov 2012

Latest

Aging Cell5 Oct

SIRT3 deficiency decreases oxidative metabolism capacity but increases lifespan in male mice under caloric restriction

Experiments in miceFatty acid β-oxidation

Molecular Cell29 Nov

Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome

Experiments in miceDietary restriction

Aging Cell9 Jul

Calorie restriction alters mitochondrial protein acetylation

Experiments in animalsDietary restriction