Mitochondrial double-stranded RNA
2 papers3 findings
- Humans1
Upstream
2Alzheimer's disease
upin humans1
1 study
Alzheimer's disease
upin humans1
Alzheimer's disease increases mitochondrial double-stranded RNA in humans.
“In AD brains, mt-dsRNA accumulation was further increased and correlated with cognitive impairment, neuropathological severity, and AD risk genotypes.”
HumansAlzheimer's diseasebrain
Mitochondrial double-stranded RNA accumulation in brain aging and Alzheimer's disease
bioRxiv : the preprint server for biology4 Feb 2026Preprint
Brain aging
upin humans1
1 study
Brain aging
upin humans1
Brain aging increases mitochondrial double-stranded RNA in humans.
“mt-dsRNA accumulated after midlife and coincided with reduced expression of mitochondrial RNA processing and translation machinery”
Humansbrain
Mitochondrial double-stranded RNA accumulation in brain aging and Alzheimer's disease
bioRxiv : the preprint server for biology4 Feb 2026Preprint
Associations
1Cognitive impairment
upin humans1
1 study
Cognitive impairment
upin humans1
Mitochondrial double-stranded RNA is associated with cognitive impairment in humans.
“correlated with cognitive impairment, neuropathological severity, and AD risk genotypes”
HumansAlzheimer's diseasebrain
Mitochondrial double-stranded RNA accumulation in brain aging and Alzheimer's disease
bioRxiv : the preprint server for biology4 Feb 2026Preprint