Microglial subtype composition

Age is associated with microglial subtype composition in mice.

“The Young SCI group exhibited a higher proportion of Homeostatic microglia and Inflammatory microglia A, whereas the old SCI group had more Inflammatory Microglia B”

Animalsfollowing spinal cord injurymicroglia

scRNA-Seq reveals age-dependent microglial evolution as a determinant of immune response following spinal cord injury

Brain research bulletin·6 Nov 2024