Microglial expression

Biomarker

1 paper1 finding

  • Animals1

Associations

1

Outcome devaluation performance

downin mice1

1 study
  1. Microglial expression is associated with outcome devaluation performance in mice.

    “increased microglial expression in the dorsal CA1 region of the hippocampus was associated with poorer outcome devaluation performance on initial tests”

    Animalsdorsal CA1 region of the hippocampusinitial tests

    Goal-directed action is transiently impaired in an hAPP-J20 mouse model of Alzheimer’s disease, and in aging male mice regardless of genotype

    bioRxiv (Cold Spring Harbor Laboratory)Jul 25, 2022Preprint

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Aging Cell

Mitochondrial DNA and age shape retinal changes in mice

Experiments in mice with matching nuclear DNA but different mitochondrial DNA linked aging to changes in retinal energy-producing proteins and immune signaling.Experiments in mice with matching nuclear DNA but different mitochondrial DNA linked aging to changes in retinal energy-producing proteins and immune signaling.

Mouse studyMitochondrion