Ecology and Evolution·May 7Epigenetic Clock in Bears: A Simple Cost-Effective Blood DNA Methylation-Based Age Estimation Method Applicable to Multiple Bear SpeciesExperiments in animalsBiomarkersPaper
Genome Biology·Apr 23Weighted 2D-kernel density estimations provide a new probabilistic measure for epigenetic ageComputational studyEpigenetic agePaper
Epigenetics & Chromatin·Apr 2Genome-wide DNA methylation patterns in Daphnia magna are not significantly associated with ageExperiments in model organismsDNA methylationPaper
Lung Cancer Management·Apr 1The association between blood-based HYAL2 methylation and early-stage lung cancer: a case-control studyCase-control study in peopleLung cancerPaper
Urolithiasis·Mar 30Klotho alleviates oxidative stress and mitochondrial dysfunction through the Nrf2/HO-1 pathway, thereby reducing renal senescence induced by calcium oxalate crystalsExperiments in miceNRF2–KEAP1 antioxidant responsePaper
Electrophoresis·Mar 27A SNaPshot Assay for Epigenetic Age Prediction of Costal CartilageCross-sectional study of 136 peopleBiomarkersPaper
American Journal of Physiology Lung Cellular and Molecular Physiology·Mar 20DNA methylation as a driver of lung fibroblast senescence in COPDCase-control study of 11 peopleDNA methylationPaper
Electrophoresis·Mar 18Forensic Age Estimation From Blood Samples by Combining DNA Methylation and MicroRNA Markers Using Droplet Digital PCRCross-sectional study of 132 peopleBiomarkersPaper
Archives of Gerontology and Geriatrics·Mar 7The association of DNA methylation-based epigenetic age acceleration with facial expression recognition in older adultsCross-sectional study in peopleEpigenetic agePaper
Steroids·Mar 417β-estradiol delays cardiac aging through suppressing the methylation of Beclin1 in a murine modelExperiments in miceEstradiolPaper
Gynecological Endocrinology·Feb 26Reduced DNMT1 expression associated with TP53 promoter hypomethylation mediate enhanced granulosa cell senescence during ovarian agingStudy in peopleCellular senescencePaper
Clinical Nutrition·Feb 23Obesity-related osteopontin protein and methylation blood levels are differentially modulated by a very low-calorie ketogenic diet or bariatric surgeryNon-randomized trial in peopleBariatric surgeryPaper
Forensic Science International·Feb 22Reproducibility and validation of a targeted and flexible epigenetic clock for forensic applicationsCohort study of 201 peopleEpigenetic clockPaper
American Journal of Physiology Lung Cellular and Molecular Physiology·Feb 20Epigenetic age acceleration in idiopathic pulmonary fibrosis revealed by DNA methylation clocksCase-control study in peoplePhenoAgePaper
Molekuliarnaia Biologiia·Feb 19New Epigenetic Markers of Age-Dependent Changes in the Cardiovascular SystemCross-sectional study in peopleBiomarkersPaper
GeroScience·Feb 10The role of protective genetic variants in modulating epigenetic agingCohort study of 14,669 peopleMechanismsPaper
Scientific Reports·Feb 4Enhancing epigenetic aging clocks in cetaceans: accurate age estimations in small endangered delphinids, killer whales, pilot whales, belugas, humpbacks, and bowhead whalesComputational studyBiomarkersPaper
PLOS One·Jan 30Genome-wide DNA methylation and transcriptome sequencing analyses of lens tissue in an age-related mouse cataract modelExperiments in miceDNA methylationPaper
Biomedicine & Pharmacotherapy·Jan 20NLRP3 promoter methylation as a predictive biomarker for glucocorticoid response in patients with inflammatory bowel diseaseCohort study of 94 peopleInflammatory bowel diseasePaper
GeroScience·Dec 28Human brain aging is associated with dysregulation of cell type epigenetic identityCross-sectional study in peopleMechanismsPaper
bioRxiv·Dec 27Human Brain Aging is Associated with Dysregulation of Cell-Type Epigenetic IdentityPreprint: cross-sectional study in peopleMechanismsPaper
bioRxiv·Dec 22An epigenetic clock for Xenopus tropicalis reveals age-associated sites enriched in H4K20me3-marked heterochromatinPreprint: experiments in animalsBiomarkersPaper
Forensic Science International Genetics·Dec 19Independent evaluation of an 11-CpG panel for age estimation in bloodCross-sectional study of 148 peopleBiomarkersPaper
PLOS One·Dec 16Impact of combined exercise on blood DNA methylation and physical health in older women with obesityNon-randomized trial in 41 peopleCombined aerobic and resistance trainingPaper
Cancer Prevention Research·Dec 10Biological Age Acceleration and Colonic Polyps in Persons under Age 50Cohort study of 51 peopleGrimAgePaper
Omics·Nov 25Age-Related Hearing Impairment: Genome and Blood Methylome Data Integration Reveals Candidate Epigenetic BiomarkersGenetic association study in peoplePresbycusisPaper
Methods in Molecular Biology·Nov 24DNA Methylation Analysis by Bisulfite Pyrosequencing of Mouse Embryonic Fibroblasts with Reprogramming Enhanced by Thyroid HormonesStudy protocolInterventionsPaper
BMC Genomics·Nov 5Increased DNMT1 acetylation leads to global DNA methylation suppression in follicular granulosa cells during reproductive aging in mammalsExperiments in miceDNA methylationPaper
Scientific Reports·Oct 29Hypertension and global DNA methylation: a population-based study in rural, Punjab, IndiaCase-control study of 900 peopleHypertensionPaper