2 papers1 finding
estiMAge
upin silico1
estiMAge predicts methylation age in silico.
“We show that estiMAge can accurately predict the ages of young and old hepatocytes”
In silicoin single cellsliver
estiMAge: development of a DNA methylation clock to estimate the methylation age of single cells
Bioinformatics advancesJan 16, 2025
National Institute on AgingUS$236.8k
GrimAge2, a DNA-based aging measure, statistically accounted for up to 52% of associations between social factors and deaths from any cause.GrimAge2, a DNA-based aging measure, statistically accounted for up to 52% of associations between social factors and deaths from any cause.
In a preprint analyzing epigenome-wide data from thousands of U.S. veterans, posttraumatic stress disorder was significantly associated with accelerated DNA methylation…In a preprint analyzing epigenome-wide data from thousands of U.S. veterans, posttraumatic stress disorder was significantly associated with accelerated DNA methylation aging.
Cell counts explain less variation in age acceleration and only modestly affect its links to mortality and 176 incident health outcomes.Cell counts explain less variation in age acceleration and only modestly affect its links to mortality and 176 incident health outcomes.