In 6,896 adults, the index scored 0.893 for predicting death within three years, outperforming three existing age and health measures.In 6,896 adults, the index scored 0.893 for predicting death within three years, outperforming three existing age and health measures.
In progeroid mice, activating the GPR81 receptor with the agonist CHBA reduced arterial lipid buildup, lowered cellular senescence, and improved endothelial integrity.In progeroid mice, activating the GPR81 receptor with the agonist CHBA reduced arterial lipid buildup, lowered cellular senescence, and improved endothelial integrity.