Metabolic age
Biomarker2 papers5 findings
In a human study of adults with type 2 diabetes, obesity increases metabolic age, which is associated with waist-to-height ratio and, in women, muscle mass, but has no effect on fasting blood glucose.
- Humans2
Effects
1Fasting blood glucose
no changein humans1
1 study
Fasting blood glucose
no changein humans1
Metabolic age has no effect on fasting blood glucose in humans (p > 0.05).
Humansin adults with type 2 diabetes mellitus
Association Between Obesity Severity and Bioelectrical Impedance Analysis-Derived Metabolic Age in Individuals with Type 2 Diabetes Mellitus · Metabolites · 16 Sep 2026
Upstream
1Obesity
upin humans1
1 study
Obesity
upin humans1
Obesity increases metabolic age in humans (p < 0.001).
Humansin individuals with type 2 diabetes mellitus
Association Between Obesity Severity and Bioelectrical Impedance Analysis-Derived Metabolic Age in Individuals with Type 2 Diabetes Mellitus · Metabolites · 16 Sep 2026
Associations
3Muscle mass
downin humans1
1 study
Muscle mass
downin humans1
Muscle mass is associated with metabolic age in humans.
Humansin female adults with type 2 diabetes mellitusfemales
Association Between Obesity Severity and Bioelectrical Impedance Analysis-Derived Metabolic Age in Individuals with Type 2 Diabetes Mellitus · Metabolites · 16 Sep 2026
Waist-to-height ratio
upin humans1
1 study
Waist-to-height ratio
upin humans1
Waist-to-height ratio is associated with metabolic age in humans.
Humansin adults with type 2 diabetes mellitus
Association Between Obesity Severity and Bioelectrical Impedance Analysis-Derived Metabolic Age in Individuals with Type 2 Diabetes Mellitus · Metabolites · 16 Sep 2026
Vitamin D
downin humans1
1 study
Vitamin D
downin humans1
Vitamin D is associated with metabolic age in humans (r = -0.254, p = 0.001).
Humansn = 164
Independent Associations of Vitamin D Levels with Visceral Fat and Metabolic Age in Adults: A Retrospective Cross-Sectional Study · Metabolites · 31 Jul 2026
Funding
National Institute on AgingUS$604.1k1 grant since 2023
Latest
17Aged human muscle secretes an enzyme that impairs stem cell maintenance
Profiling conditioned media revealed that altered sphingolipid signaling reduces muscle stem cell pools in human cell cultures.Profiling conditioned media revealed that altered sphingolipid signaling reduces muscle stem cell pools in human cell cultures.