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Mean TRF length

Biomarker

1 paper2 findings

  • Humans1

Interventions

1

Hemodynamic stress

downin humans1

1 study

  1. Hemodynamic stress decreases mean TRF length in humans (102 bp/yr vs. 47 bp/yr, P < 0.05).

    “there was a significantly greater rate of decrease for cells from iliac arteries than from iliac veins (102 bp/yr vs. 47 bp/yr, respectively, P < 0.05)”

    Humansiliac artery

    Telomere length and replicative aging in human vascular tissues

    Proceedings of the National Academy of Sciences of the United States of America21 Nov 1995

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Upstream

1

Cell cycle regulation

downin human cells1

1 study

  1. Cell cycle regulation decreases mean TRF length in human cells.

    “Mean TRF length decreased as a function of population doublings in human endothelial cell cultures from umbilical veins, iliac arteries, and iliac veins.”

    Cellsendothelium

    Telomere length and replicative aging in human vascular tissues

    Proceedings of the National Academy of Sciences of the United States of America21 Nov 1995

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