LysoTracker signal intensity and signal-positive area per cell

1. Cellular senescence is associated with LysoTracker signal intensity and signal-positive area per cell in humans.

   “Representative outcomes show higher acidotropic fluorescent dye signal and larger lyso-positive regions in late-passage cultures than in early-passage controls”

   ReviewLate-passage cultures compared with early-passage controlsIMR-90 human lung fibroblasts

   Lysosomal Profiling With LysoTracker For Quantitative Assessment of Cellular Senescence In Human Fibroblasts

   Journal of visualized experiments : JoVE·17 Jul 2026

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